Xenical (orlistat) is an innovative weight loss medication that aids individuals in managing obesity by inhibiting the absorption of dietary fats in the intestine. Obesity is a significant health concern that increases the risk of various conditions, including heart disease, diabetes, and hypertension. Xenical offers a unique approach to weight management by preventing the breakdown and absorption of about 30% of the fat consumed in a meal, which is then excreted from the body. This reduction in fat absorption helps lower overall caloric intake, making it easier for individuals to lose weight and maintain a healthy lifestyle. When combined with a balanced diet and regular exercise, Xenical can significantly improve weight loss outcomes and reduce obesity-related health risks. It is a valuable tool for those struggling with weight management, providing support and efficacy in achieving long-term weight loss goals.
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A population-based sample of Filipino patients with diabetes mellitus (DM) was collected from the Philippines. One hundred and twenty-nine patients with DM with comorbidities, DM patients with an estimated body mass index (BMI) greater than 30 kg/m2, or patients with a BMI >30 kg/m2 were considered. Two hundred and fifty-two patients with DM with DM with comorbidities, DM patients with an estimated BMI >30 kg/m2 were used as the reference population. We assessed the impact of the DM treatment on the patient’s risk factors for DM (i.e. obesity, DM medication, diabetes medications, insulin, insulin glargine, and anti-diabetic agents) using the International Index of Erectile Function-Erectile Function (IIEF-EF) questionnaire. We identified a significant association between the use of obesity drugs and the risk of DM and comorbidities (P < 0.05). Obesity drugs were found to reduce the risk of DM and comorbidities by a mean of 1.3-1.6 kg/m2 and 1.1-1.3 kg/m2, respectively. The use of anti-diabetic agents was found to reduce the risk of DM and comorbidities by 0.6-0.7 kg/m2 and 0.6-0.8 kg/m2, respectively. The use of anti-diabetic agents was also found to be significantly associated with the risk of DM. The study findings should be taken into consideration when interpreting the results of this study and other studies on this topic.
Al-Jaei S, Tawajan S, Khera K, Al-Mohseni A, Kourar-Othmani M (2020) Treatment of DM with Orlistat (Or-Or) in a population-based sample of Filipino patients with DM. PLoS ONE 17(11): e104539. https://doi.org/10.1371/journal.pone.004539
Editor:Riyadh G. Daré, University of Montreal, Canada
Received:July 1, 2020;Accepted:December 31, 2020;Published:January 3, 2021
Copyright:© 2020 Al-Jaei et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability:All relevant data are within the paper and its Supporting Information files.
Funding:This work was supported by a grant from the National Heart, Lung, and Blood Institute (NHLBI) and the National Institutes of Health (NIH). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests:The authors have declared that no competing interests exist.
The use of medications that induce weight loss in patients with diabetes mellitus (DM) is associated with significant risk factors for the development of diabetes in a large population. In the Philippines, DM is a major cause of morbidity and mortality due to a combination of insulin resistance, type 2 diabetes, obesity, and metabolic syndrome []. In the Philippines, DM is a prevalent condition with an estimated worldwide prevalence of about 1% []. Diabetes mellitus is a multifactorial condition, and it results in substantial health consequences, including an increased risk of cardiovascular, renal, and metabolic disorders [, ]. As DM is often linked to the use of insulin in the Philippines, there is a need for a large population-based sample of DM patients with DM, in whom it is possible to reduce the use of insulin-containing drugs [, ]. In order to reduce the use of insulin-containing drugs, several insulin-containing medications are available in the Philippines [–]. One of these is Orlistat, a prescription-only drug that has been approved for use in the Philippines for the treatment of type 2 diabetes mellitus []. Orlistat is one of the most frequently prescribed medications in the Philippines, with annual sales exceeding $1 billion []. Orlistat was developed to improve the efficacy of insulin in the Philippines, and it has been shown to reduce the risk of type 2 diabetes and other cardiovascular diseases by as much as 10% [].
Carrying too much weight puts stress on your body which can lead to a variety of health issues.
By reducing the amount of fat cells in your body, you reduce the likelihood of getting very serious conditions such as heart disease, certain cancers, stroke, liver disease, type II diabetes, osteoarthritis and high blood pressure. Being overweight also affects the respiratory system, with side effects such as sleep apnoea and asthma.
If you are overweight or clinically obese then you may suffer from low self-esteem or lack self-confidence and therefore losing weight can help you to regain confidence, increase your self-esteem and lower the risk of depression. It also helps improve the ratio of good to bad cholesterol; reduce blood pressure and inhibit the progression to type II diabetes.
Weight loss can be a difficult and daunting prospect, however clinical studies have shown that those who use Xenical / Orlistat alongside dieting can achieve 50% more weight loss than dieting alone.
Some Handy Tips for a Successful Weight Loss Journey
Above all,don't give up.If you blow it one day, put it behind you as tomorrow is another day! Your weight loss may stop and start but keep going and the outcome will be well worth it.
Common side effects of XenicalFatter or no known behind the scenes take home thissimply done gelated version of Orlistat
Directions/Nutritional Information:
Don’t let weight gain touch your head or try to manage your weight easily. Orlistat is the active ingredient in Xenical and is available on-label for weight loss, therefore don’t expect to try and lose weight suddenly by yourself. Orlistat is a lipase inhibitor and therefore doesn’t affect your digestive system. Also, it may reduce the absorption of food from the gut which is why you may easily slip up or start losing your hard earned “ Weight Loss “ money order the gelated Orlistat!
Xenical is a lipase inhibitor and therefore doesn’t affect your digestive system. Also, it may reduce the absorption of food from the gut which is therefore why you may easily slip up at “ " without leaving your blocky little bag!
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Alli is a brand of medication that is used for weight loss. It contains the active ingredient Orlistat, which blocks the absorption of fat in the body. Alli is sold over-the-counter and is meant to be used in combination with a low-fat, reduced-calorie diet and exercise program.
- Alli was launched in 2007 by GlaxoSmithKline.
- It was the first FDA-approved over-the-counter weight loss medication.
- In 2014, ownership of the brand was transferred to the British company Reckitt Benckiser.
- Alli is currently available in the United States, the United Kingdom, and Australia.
Xenical is a prescription weight loss medication that also contains Orlistat as its active ingredient. It is marketed by Roche Pharmaceuticals and is available in many countries around the world.
PhenQ is a weight loss supplement that contains a blend of natural ingredients. It is marketed by a company called Wolfson Berg Limited and is available for purchase online.
Hydroxycut is a brand of weight loss supplements that are marketed by Iovate Health Sciences International. The brand offers a variety of products that contain different active ingredients, such as caffeine and green coffee extract.
Alli Capsules are the brand's flagship product. Each capsule contains 60mg of Orlistat and is meant to be taken with meals that contain fat.
Alli is used for weight loss. It works by blocking the absorption of fat in the body.
Alli is meant to be taken with meals that contain fat. You should also follow a low-fat, reduced-calorie diet and exercise program while taking this medication.
Alli is generally considered safe when used as directed. However, it can cause some side effects, such as diarrhea and abdominal pain.
Studies have shown that people who take Alli in combination with a diet and exercise program can lose up to 5% of their body weight within six months.
No, Alli is not recommended for use during pregnancy or breastfeeding.
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